Reverse transcriptase, also known as RNA-dependent DNA polymerase, is a DNA polymerase enzyme that transcribes single-stranded RNA into DNA. Common reverse transcriptases are M-MLV and AMV, among which M-MLV is better than AMV. But conventional RT enzymes have two active sites, one executing the polymerase activities and another executing the ribonuclease H activity. Yeasen has carried out directional modification on reverse transcriptase, which removes RNase H activity, thereby improving the ability of cDNA synthesis. Using protein evolution technology to improve the thermostability of reverse transcription. Yeasen's reverse transcriptase not only has strong synthesis ability but also a strong tolerance ability. In addition, Yeasen has strict requirements on quality. It is the best choice for reverse transcriptase.