CTP Tris Solution GMP-grade (100 mM)

Details:

Description

CTP, Cytidine-5'-triphosphate, can be used in a variety of molecular biology applications, such as in vitro transcription, RNA amplification, and the synthesis of choline and ethanolamine.
This product is a transparent colorless aqueous solution prepared from CTP trisodium salt, and free from DNase, RNase and phosphatase contamination.
This product is produced in accordance with GMP process requirements and provided in liquid form.

Feature

  • Validated, product-specific process and analytical methods
  • Product-specific stability
  • Documentation follows applicable GMP guidelines
  • AOF production process and raw materials (TSE & BSE) 
  • Nitrosamine statement
  • Regulatory support documents available
  • Large-scale production
  • The increased IVT yield and the decreased dsRNA content under the optimized Tris NTP reaction system

Application

  • RNA synthesis and amplification
  • Building block for in vitro transcription

Specification

CAS No 65-47-4 (free acid)
Formula C9H16N3O14P3 (free acid)
Molecular weight 483.16 g/moL (free acid)
Purity(HPLC) ≥ 99%
Content 100 mM ± 3 mM
Structure

Component

Components No. Name 10653ES03 10653ES08 10653ES25 10653ES76
10653 CTP Tris Solution GMP-grade (100 mM) 1 mL 5 mL 25 mL 500 mL

Storage

The product should be stored at -25℃ ~ -15℃ for two years.

Figures

  • Increased the IVT yield

Figure 1. The IVT yield was significantly increased under the optimized Tris NTP reaction system, compared with the sodium NTP reaction system.

  • Decreased the dsRNA content

Figure 2. The content of dsRNA was significantly decreased under the optimized Tris NTP reaction system, compared with the sodium NTP reaction system. The content of dsRNA was detected by Dot Blot method.

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