Product Description

Spectinomycin hydrochloride, an amino cyclic alcohol antibiotic, has a strong inhibitory effect on both Gram-positive and Gram-negative bacteria. Its antibacterial principle is that it can bind to the 30S subunit of bacterial ribosome and inhibit protein synthesis and extension by interfering with the translocation of peptide tRNA. The mutation of rpsE in ribosomal protein 5S gene can prevent the binding of spectinomycin hydrochloride and produce resistance to the antibiotic.

In cell culture, spectinomycin hydrochloride can be used as an antibacterial agent and a screening drug for screening resistant Escherichia coli or plant cells. It can be prepared into a storage solution of 10 mg/mL after 0.22 μM filter membrane, filter and sterilize, sub pack, and freeze at -20℃. 

Product Properties

Synonyms	Togamycin dihydrochloride pentahydrate; Actinospectacin dihydrochloride pentahydrate; Espectinomicina dihydrochloride pentahydrate
CAS#	22189-32-8
Molecular Weight	405.3 g/mol
Molecular Formular	C14H24N2O7 ·2HCl
Appearance	White crystal or powder
Activity Melting Point	>737 μg/mg 205-207℃
Purity	> 98 %
Solubility	Dissolve in water (50 mg/mL), methanol，DMSO (~11 mg/mL)， ethanol (~0.3 mg/mL)，DMF (~2 mg/mL).
Structure

Shipping and Storage

The product component is shipped with ice pack and can be stored at 2-8℃ for 2 years.

Cautions

1) The solution cannot be autoclaved.

2) For your safety and health, please wear experimental clothes and disposable gloves.

3) This product is only used for scientific research.