Description

UTP, Uridine-5'-triphosphate, can be used in a variety of molecular biology applications, such as in vitro transcription, RNA amplification, siRNA synthesis, etc. In addition, UTP is involved in galactose metabolism. The activated form of UDP-galactose is converted to UDP-glucose, which participates in the glycogen synthesis pathway.
This product is a transparent colorless aqueous solution prepared from UTP tris solution, and free from DNase and RNase contamination.
This product is produced in accordance with GMP process requirements and provided in liquid form.

Feature

• Validated, product-specific processes and analytical methods
• Product-specific stability
• Documentation follows applicable GMP guidelines
• AOF production process and raw materials (TSE & BSE) 
• Nitrosamine statement
• Regulatory support documents available
• Large-scale production
• The increased IVT yield and the decreased dsRNA content under the optimized Tris NTP reaction system

Application

• RNA synthesis and amplification
• Building block for in vitro transcription

Specification

CAS No	63-39-8 (free acid)
Formula	C9H15N2O15P3 (free acid)
Molecular weight	484.14 g/moL (free acid)
Purity(HPLC)	≥ 99%
Content	100 mM ± 3 mM
Structure

Component

Components No.	Name	10654ES03	10654ES08	10654ES25	10654ES76
10654	UTP Tris Solution GMP-grade (100 mM)	1 mL	5 mL	25 mL	500 mL

Storage

The product should be stored at -25℃ ~ -15℃ for two years.

Figures

• Increased the IVT yield

Figure 1. The IVT yield was significantly increased under the optimized Tris NTP reaction system, compared with the sodium NTP reaction system.

• Decreased the dsRNA content

Figure 2. The content of dsRNA was significantly decreased under the optimized Tris NTP reaction system, compared with the sodium NTP reaction system. The content of dsRNA was detected by the Dot Blot method.